HH5561 Health Economics and Decision Modelling Assignment, UOG, UK

University University of Glasgow (UOG)
Subject HH5561 Health Economics and Decision Modelling

The assignment involves analyzing a decision model provided in Excel worksheets. Key tasks include:

  1. Programming the Decision Model
    • Use the provided structure and data for a stylized testing intervention.
  2. Performing Sensitivity Analysis
    • Assess how different inputs influence the model’s outcomes.
  3. Reporting Results
    • Write a short report summarizing findings from the model and analysis.

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Submission Details

  • Report Word Limit: Up to 1,000 words, divided into:
    • Results (~800 words): Present base case results and sensitivity analysis.
    • Conclusions (~200 words): Provide decision-making insights based on the analysis.
    • References: Use Harvard Referencing Style consistently.
  • Formatting Guidelines:
    • Use clear headings, tables, and figures where necessary.
    • Ensure tables and figures contribute to the analysis and are legible.
    • Avoid redundant data in visual elements.

Worksheets Provided

  1. Introduction: Overview of assessment details.
  2. Conceptual Model: Diagram of a decision tree representing the model structure.
  3. Data: Input parameters for the model, including clinical, cost, and outcome details.

Decision Problem

  • Population: Patients admitted to hospital with suspected severe infection.
  • Intervention: Adding a test to the clinical pathway to guide antibiotic use.
  • Comparator: Existing clinical practice without the test.
  • Outcomes: Costs, Quality Adjusted Life Years (QALYs), incremental cost-effectiveness ratio (ICER), and incremental monetary net benefit (INMB).

Model Summary

  • Structure: Decision tree.
  • Time Horizon: 12 months.
  • Perspective: Health care payer (Canadian dollars).
  • Follow-up Periods:
    • 1 Month: Assess outcomes post-hospital stay.
    • 12 Months: Evaluate infection resolution and symptoms.
  • Potential Patient States:
    • Alive (with/without complications).
    • Dead (with/without antibiotics)

Clinical Parameters

 

Parameter Value (Mean) Standard Error Notes
Mortality
Baseline (current practice) 0.15 0.02 1-month follow-up
RR (Testing strategy) 0.9 0.03
Mortality after complications 0.3 0.06 12-month follow-up
Mortality (no complications) 0.05 0.01
Complications
Baseline (current practice) 0.25 0.04
RR (Testing strategy) 0.75 0.12
Antibiotic Initiation
Baseline (current practice) 0.85 0.07
RR (Testing strategy) 0.65 0.09

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Cost Parameters (CAN $)

 

Parameter Value (Mean) Standard Error Notes
Testing Costs $250.00 NA
Antibiotics $50.00 NA
Inpatient Stay (Complications) $17,500.00 500 At 1 month
Inpatient Stay (Patient Died) $12,500.00 350 At 1 month
Inpatient Stay (No Complications) $4,500.00 300 At 1 month

Outcome Parameters

 

Parameter Value (Mean) Standard Error Notes
Alive at 1 Month (QALY) 0.1 NA
Alive at 12 Months (QALY) 0.75 NA
QALY Decrement for Complications -0.05 NA

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