- BUSI 1475: Your task is to identify and select an article from the BBC News website (news.bbc.co.uk): Management in a Critical Context Course Work, UOG, UK
- UMACTF-15-M: You have recently been appointed as a Financial Analyst for a leading investment bank in London: Corporate Financial Strategy Course Work, UWE, UK
- BAM5010: choose an organisation and make some recommendations for the delivery: Work Based Project Course Work, UOB, UK
- You are required to calculate ratios for Fresh Farms Ltd: financial Course Work, UK
- Understand the legal, ethical and theoretical context for health, safety and risk management: leadership and Management Course Work, UK
- P3 Describe the types of training and development used by a selected business: BTEC Business Extended Diploma Pearson Course Work, UK
- Describe how a selected business identifies training needs: BTEC Business Extended Diploma Pearson Course Work, UK
- Discuss your chosen business, background information and why you have chosen that business: BTEC Business Extended Diploma Pearson Course Work, UK
- Activity 7: Risk management in an organisation should be both sensible and proportionate to the level of risk involved: NEBOSH IDIP ID1 Research Paper Course Work, OU, UK
- Activity 6: Reviewing health and safety performance Critique your chosen organisation’s health and safety: NEBOSH IDIP ID1 Research Paper Course Work, OU, UK
- Activity 5: Management of contractors Review how your chosen organisation selects contractors and manages them while they are on site: NEBOSH IDIP ID1 Research Paper Course Work, OU, UK
- Activity 2: Preparing a brief research report on approaches to worker consultation: NEBOSH IDIP ID1 Research Paper Course Work, OU, UK
- Create an organisational risk profile for your chosen organisation: NEBOSH IDIP ID1 Research Paper Course Work, OU, UK
- Explain the differences between learning requirements and continuous professional development: Leadership and Management Assignment, UL, UK
- What steps, component parts and enabling tools would you use to develop a therapy: Advanced therapeutic medicinal products Course Work, TUM, UK
- CS3DS19: Construct a KNIME workflow to understand the data characteristics and quality, report: Data Science Algorithms and Tools Course Work, UOW, UK
- Explain how principles of support are implemented in health and social care practice: Diploma In Health And Social Care Level 5 Course Work, UK
- The UK Manufacturing UK LTD is facing an array of issues that require a sound understanding: Management Decision Making Assignment, USM, UK
- Identify sources of information and guidance about how to support a child or young person: child care diploma level 3 Course Work, OU, UK
- Explain why it is important to take full account of a child or young person’s level of understanding: Child care diploma level 3 Course Work, OU, UK
What are the advantages of performing image processing calculations in reciprocal space over real space: Biological Sciences Course Work, OBU, UK
| University | Oxford Brookes University (OBU) |
| Subject | Biological Sciences |
1.
a) What are the advantages of performing image processing calculations in reciprocal space over real space? Which operations are better done in real space, and which are better done in reciprocal
space?
b) What are the major considerations in preparing biological samples for cryo-EM?
c) Explain the differences between an isosurface view, a projection, and a density section.
2.
a) What are the important considerations for the characteristics of electron detectors to be used in
high-quality data collection? Explain why the considerations you have chosen are important.
b) What are the main microscope factors that affect the quality of cryo-EM images and how are their
effects corrected?
c) What are the main sample factors that determine the quality of the final results, and how can the common problems be addressed?
3.
a) When carrying out image processing in 2D, how can (i) the signal-to-noise ratio and (ii) the contrast in cryo-EM be improved? Why is this necessary?
b) Define the point spread function (PSF) and the contrast transfer function (CTF). Explain how they are related, and explain how they can be used in cryo-EM image analysis.
4.
a) Explain the principles and image processing steps for determining a 3D density map from TEM single-particle images in the case of an unknown structure.
b) Discuss how you would establish if the details of the experimentally determined map are correct.
5. What are the key considerations in determining the in situ structure of a cellular complex that is assembled only in its native cellular environment?
Your answer should take into account sample preparation, data collection, and image processing aspects. Think about what compromises might be needed to optimize the result and explain the reasons for your choices.
6. Explain how you would fit an atomic model to a cryo-EM map and how you would validate your fit, for a map at
Do You Need Assignment of This Question
Grab our top-rated coursework writing help from the experts of Students Assignment Help UK. Our professional experts have sound knowledge and incredible writing skills. You can also hire do my assignment for me service on Biological Sciences to get HD rank at a low cost.
Answer
