- BST851 Business Data Analytics Assessment Coursework 2026
- MMM143 International Business and the World Economy Coursework 2026
- EMS402U Engineering Design Coursework Project Report 2026 | QMUL
- 25BSC565 Fundamentals of Strategic Management Coursework Brief
- MARK5025 Contemporary Marketing Communications Assessment Coursework Brief 2
- GEEN1127 Design and Materials Individual Coursework Brief 2025-2026 | UOG
- BPS319 PBL 3 Natural Product Chemistry vs Kinetic Isotope Effects Coursework | UOL
- LD7098 Cyber Security Principles Coursework Assessment 2025-26 | Northumbria University
- EG7004 Soil Structure Engineering Assignment 1 Coursework Semester A 2025/26 | University of East London (UOEL)
- BSC127 Information and Knowledge Management Individual Coursework | Loughborough University
- CI5250 Computing Systems Assignment – Networking Design Coursework | Kingston University
- Critical Literature Review Assignment 001 Coursework | Harvard University
- AFE_5_TAP Taxation Practice Assignment Coursework | London South Bank University
- EEEE3083 Power Electronic Aplications and Control Assessment Coursework 1 Individual Report | University of Nottingham
- 7BUIS008W Data Mining & Machine Learning Individual Coursework
- DFI4002 Introduction to Finance Assessment Essay Coursework – Arden University
- CPD Planned Learning Form – Overseas Pharmacists Assessment Programme (OSPAP) Coursework
- CMP-L0170 Level 7 Computer and Operating Systems Assessment Coursework portfolio
- IF1201 Assignment: Developing Financial and Utility Tools Using VBA in Excel
- MA12009 Exploratory Data and Statistical Analysis of Airbnb and Spotify Datasets
CHEM1110: You are working within the pharmaceutical industry, and you have been assigned a kinase to develop an inhibitor: Computational and Medicinal Chemistry Exercise Course Work, IUB, UK
| University | Islamia University Bahawalnagar (IUB) |
| Subject | CHEM1110: Computational and Medicinal Chemistry Exercise |
You are working within the pharmaceutical industry, and you have been assigned a kinase to develop an inhibitor for. Your team has already found a compound that can moderate the activity of the kinase of interest
- Using this information, use Auto DockTools and Autodock Vina to dock your compound with the kinase of interest. Your report should include
a) A brief explanation of how you determine the search area for the docking, accompanied by a suitable picture to show where the search box is located with respect to the kinase in your docking.
b) Description of possible interactions between your compound and the kinase that you have identified after docking, accompanied by a suitable picture(s) and labeling to highlight the interactions.
c) A table to show the binding affinity of your compound and the kinase from docking
- Based on the results from the molecular docking, and also using your knowledge of medicinal chemistry, suggest FIVE changes you would make to the molecule in order to probe SAR and increase binding efficiency.To answer this question, please draw your target molecule, and highlight the proposed changes with a brief explanation as a note as to the reasons for the change with the suspected outcome(s). Your answer should be a maximum of ONE A4 page in length.
Do You Need Assignment of This Question
Struggling to complete your BTEC assignments? Students Assignment Help UK offers a team of veteran, knowledgeable BTEC writers to provide assistance with every stage of the assignment process. From researching and writing to proofreading and editing, our experts will make sure that all requirements are met for an exceptional outcome. Contact us today for reliable online assignment help in the UK!
Answer
